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FPNC Research
 

Our physicians are passionate and involved specialists, teaching in regional universities and medical centers, participating in national organizations that monitor and set the standards for reproductive medicine, publishing and presenting frequently, and participating in research to further the knowledge and treatment of infertility.

The collection on this page includes some of the more popular samples of the research conducted and articles authored by our physicians.

Ongoing Research Studies

Fertility Physicians Research Study for Patients Undergoing IVF Progesterone-IBSA vs. Endometrin®

Progesterone supplementation during the second half of IVF treatment improves pregnancy rates. Currently, IVF treatment employs progesterone given by deep injection or placed in the vagina.

An experimental progesterone supplement, Progesterone-IBSA, is given by subcutaneous injection. Progesterone-IBSA has been used in Europe but not yet in the United States.

We are pleased to offer our patients the opportunity to participate in a nationwide trial comparing this experimental progesterone to another progesterone supplement that is placed within the vagina (Endometrin®).

For patients participating in the study, the experimental progesterone medication will be supplied, free of charge, amounting to a savings of $1036. In addition, $1500 will be given to compensate for their time and commitment.

For further details on this study, please download this pdf document.

If you are interested in participating in this research study or would like more information, please contact:

Angie Toyama, MPH
Clinical Research Coordinator
atoyama@fpnc.com
408.356.5000
866.531.6192

AMH (Anti-Mullerian Hormone) in Reproductive-Age Women

We are currently conducting a research study to determine the normal range of values of the hormone AMH (anti-mullerian hormone) in reproductive-age women. AMH has been shown to decrease as women age. Better understanding of this hormone may provide information about a woman’s fertility potential.

To better understand the normal range of levels of this hormone in women of reproductive age, we are planning to measure this hormone in women of different ages, with and without a history of infertility. We will compare AMH values to other known markers of fertility potential in an effort to provide women with more information about their chances of conceiving.

Study participants will be compensated $25 for having a single blood draw performed. All identifying information will be removed by the researchers before analyzing the data.

If you are interested in participating in this research study or would like more information, please contact:

Angie Toyama, MPH
Clinical Research Coordinator
atoyama@fpnc.com
408.356.5000
866.531.6192


Previous Research

Anastrozole vs. Clomiphene Citrate

The purpose of this multi-center clinical trial was to evaluate the safety and tolerability of anastrozole by comparing it to clomiphene citrate, often known as Clomid® or Serophene®, in women age 18-40 with irregular menstrual cycles undergoing an ovulation induction cycle. The data will be reported to the FDA to seek approval for Anastrozole's use in ovulation induction. At this time Anastrozole is indicated as a treatment for breast cancer and is prescribed "off-label" as a fertility drug.

Gonal-F vs. Fostimon:

This multi-center study evaluated the clinical efficacy and tolerability of two highly purified FSH preparations (Fostimon and Gonal-F) in women undergoing controlled ovarian stimulation for in vitro fertilization. The data will be used to seek approval from the FDA for the use of Fostimon in the United States.

  • Multicenter study to determine the efficacy of Oxiplex™ Barrier Film, which is indicated for use to prevent adhesion formation after laparoscopic gynecological surgery.
    FzioMed, San Luis Obispo, CA - Alexis Kim, MD; David Adamson, MD.
  • Multicenter study to determine efficacy and safety of AF0157 for the reduction of post-surgical adhesions after operative laparoscopy.
    Alliance Pharmaceutical, San Diego, CA - Alexis Kim, MD; David Adamson, MD.
  • Evidence based guidelines for the use of in vitro fertilization in treating endometriosis.
    American Society for Reproductive Medicine - David Adamson, MD.
  • Development of children conceived through IVF/ET and ICSI.
    University of Oregon - David Adamson, MD.